Linked Life Data

18468556

Source:http://linkedlifedata.com/resource/pubmed/id/18468556

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9-10
pubmed:dateCreated
2008-5-12
pubmed:abstractText
The zebrafish model organism is increasingly used for assessing drug toxicity and safety and numerous studies confirm that mammalian and zebrafish toxicity profiles are strikingly similar. This transparent vertebrate offers several compelling experimental advantages, including convenient drug delivery and low cost. Although full validation will require assessment of a large number of compounds from diverse classes, zebrafish can be used to eliminate potentially unsafe compounds rapidly in the early stages of drug development and to prioritize compounds for further preclinical and clinical studies. Adaptation of conventional instrumentation combined with new nanotechnology developments will continue to expand use of zebrafish for drug screening.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1359-6446
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
394-401
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Zebrafish: a predictive model for assessing drug-induced toxicity.
pubmed:affiliation
Phylonix, 100 Inman Street, Cambridge, MA 02139, USA. pat@phylonix.com
pubmed:publicationType
Journal Article, Review