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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-6-13
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pubmed:abstractText |
Liver transplantation is the primary treatment for various end-stage hepatic diseases but is hindered by the lack of donor organs and by complications associated with rejection and immunosuppression. There is increasing evidence to suggest the bone marrow is a transplantable source of hepatic progenitors. We previously reported that multipotent bone marrow-derived mesenchymal stem cells differentiate into functional hepatocyte-like cells with almost 100% induction frequency under defined conditions, suggesting the potential for clinical applications. The aim of this study was to critically analyze the various parameters governing the success of bone marrow-derived mesenchymal stem cell-based therapy for treatment of liver diseases.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10102814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10325227,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10648575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10670643,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10869283,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10917519,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-10971032,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-11179248,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-11508446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-11932747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-11996907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-12475952,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-12665832,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-12665833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-14576065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15158325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15389871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15562440,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15588504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15713913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15817682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15850839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-15975372,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-16091779,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-16724977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-16732175,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-16928726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-17295660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-17895982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-2824955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-2869522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-7082331,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-7940741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-8600162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-8831605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18455168-9047152
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2111-21, 2121.e1-3
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pubmed:dateRevised |
2011-8-1
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pubmed:meshHeading |
pubmed-meshheading:18455168-Humans,
pubmed-meshheading:18455168-Animals,
pubmed-meshheading:18455168-Mice,
pubmed-meshheading:18455168-Liver,
pubmed-meshheading:18455168-Liver Regeneration,
pubmed-meshheading:18455168-Carbon Tetrachloride,
pubmed-meshheading:18455168-Reactive Oxygen Species,
pubmed-meshheading:18455168-Bone Marrow Transplantation,
pubmed-meshheading:18455168-Hepatocytes,
pubmed-meshheading:18455168-Antioxidants,
pubmed-meshheading:18455168-Time Factors,
pubmed-meshheading:18455168-Cells, Cultured,
pubmed-meshheading:18455168-Disease Models, Animal,
pubmed-meshheading:18455168-Cell Differentiation,
pubmed-meshheading:18455168-Cell Survival,
pubmed-meshheading:18455168-Cell Proliferation,
pubmed-meshheading:18455168-Mice, Inbred NOD,
pubmed-meshheading:18455168-Liver Failure, Acute,
pubmed-meshheading:18455168-Mice, SCID,
pubmed-meshheading:18455168-Oxidative Stress
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