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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2008-5-2
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pubmed:abstractText |
Most radioimmunotherapy studies on radiolabeled antibody distribution are based on autoradiographic and radioluminographic data, which provide a lack of detailed information due to low resolution. We used fluorescently labeled anti-carcinoembryonic antigen (CEA) antibody (A5B7) to investigate quantitatively the kinetics and microdistribution of antibody in a clinically relevant orthotopic colorectal cancer model (LS174T) using high-resolution digital microscopy.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1078-0432
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2639-46
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pubmed:meshHeading |
pubmed-meshheading:18451227-Animals,
pubmed-meshheading:18451227-Antibodies, Monoclonal,
pubmed-meshheading:18451227-Antibodies, Neoplasm,
pubmed-meshheading:18451227-Blood Vessels,
pubmed-meshheading:18451227-Carcinoembryonic Antigen,
pubmed-meshheading:18451227-Colorectal Neoplasms,
pubmed-meshheading:18451227-Disease Models, Animal,
pubmed-meshheading:18451227-Fluorescent Dyes,
pubmed-meshheading:18451227-Humans,
pubmed-meshheading:18451227-Liver Neoplasms,
pubmed-meshheading:18451227-Mice,
pubmed-meshheading:18451227-Microscopy, Fluorescence,
pubmed-meshheading:18451227-Neoplasm Metastasis,
pubmed-meshheading:18451227-Radioimmunotherapy
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pubmed:year |
2008
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pubmed:articleTitle |
Microdistribution of targeted, fluorescently labeled anti-carcinoembryonic antigen antibody in metastatic colorectal cancer: implications for radioimmunotherapy.
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pubmed:affiliation |
Cancer Research UK Targeting and Imaging Group, Department of Oncology, University College London, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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