Linked Life Data

18445607

Source:http://linkedlifedata.com/resource/pubmed/id/18445607

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2008-6-16
pubmed:abstractText
Sequence-directed mapping of nucleosome positions is of major biological interest. Here, we present a web-interface for estimation of the affinity of the histone core to DNA and prediction of nucleosome arrangement on a given sequence. Our approach is based on assessment of the energy cost of imposing the deformations required to wrap DNA around the histone surface. The interface allows the user to specify a number of options such as selecting from several structural templates for threading calculations and adding random sequences to the analysis. AVAILABILITY: The nuScore interface is freely available for use at http://compbio.med.harvard.edu/nuScore. CONTACT: peter_park@harvard.edu; tolstorukov@gmail.com SUPPLEMENTARY INFORMATION: The site contains user manual, description of the methodology and examples.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1367-4811
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1456-8
pubmed:dateRevised
2010-5-10
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
nuScore: a web-interface for nucleosome positioning predictions.
pubmed:affiliation
Harvard-Partners Center for Genetics and Genomics, Brigham and Women's Hospital, Boston, MA 02115, USA. tolstorukov@gmail.com
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural