|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007034,
umls-concept:C0019409,
umls-concept:C0021469,
umls-concept:C0037098,
umls-concept:C0038784,
umls-concept:C0175921,
umls-concept:C0220781,
umls-concept:C0279516,
umls-concept:C0348080,
umls-concept:C0441655,
umls-concept:C1533691,
umls-concept:C1883254
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2008-5-26
|
|
pubmed:abstractText |
Silica sulfuric acid catalyzes efficiently the reaction of sulfonamides with both carboxylic acid anhydrides and chlorides under solvent-free and heterogeneous conditions. All the reactions were done at room temperature and the N-acylsulfonamides were obtained with high yields and purity via an easy work-up procedure. This method is attractive and is in a close agreement with green chemistry. These compounds were also investigated for antibacterial activity, including Gram-positive cocci and Gram-negative bacilli, and carbonic anhydrase II inhibitory activity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1464-3391
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
15
|
|
pubmed:volume |
16
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
5465-72
|
|
pubmed:meshHeading |
pubmed-meshheading:18439830-Anti-Bacterial Agents,
pubmed-meshheading:18439830-Carbonic Anhydrase II,
pubmed-meshheading:18439830-Carbonic Anhydrase Inhibitors,
pubmed-meshheading:18439830-Catalysis,
pubmed-meshheading:18439830-Gram-Negative Bacteria,
pubmed-meshheading:18439830-Gram-Positive Cocci,
pubmed-meshheading:18439830-Microbial Sensitivity Tests,
pubmed-meshheading:18439830-Molecular Structure,
pubmed-meshheading:18439830-Silicon Dioxide,
pubmed-meshheading:18439830-Stereoisomerism,
pubmed-meshheading:18439830-Structure-Activity Relationship,
pubmed-meshheading:18439830-Sulfonamides,
pubmed-meshheading:18439830-Sulfuric Acids
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Synthesis, in vitro antibacterial and carbonic anhydrase II inhibitory activities of N-acylsulfonamides using silica sulfuric acid as an efficient catalyst under both solvent-free and heterogeneous conditions.
|
|
pubmed:affiliation |
Department of Chemistry, Islamic Azad University, Shahreza Branch, Shahreza 86145-311, Islamic Republic of Iran. massah@iaush.ac.ir
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
