Linked Life Data

1843768

Source:http://linkedlifedata.com/resource/pubmed/id/1843768

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-3-12
pubmed:abstractText
Photopic electroretinograms, either to full-field light flashes (FERGs) or to contrast-reversal of square-wave gratings (PERGs) have been recorded in pigeons aged 2 years old (n = 5) and 10 years old (n = 5). Mydriatic pupil diameter, ophthalmoscopic appearance of the retinal fundus and optic media, and refractive state were comparable in the two groups. V/log I functions of individual FERG components (a-wave, b-wave and oscillatory potentials) displayed significantly lower slopes in the old birds than in the young, which suggests a reduction in retinal gain. PERG amplitude also was significantly lower in the older birds over a wide range of spatial frequencies (0.2-8.8 c/deg). Estimated visual acuity based on the extrapolated high-frequency cut off was 18 c/deg in the younger birds and 7.8 c/deg in the older birds. These results are in agreement with psychophysical data and retinal age-related losses in visual acuity, photoreceptors and retinal ganglion cells. Since these findings are comparable to those reported for humans, the results suggest that pigeons may serve as a useful model for human visual aging.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0042-6989
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
661-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Electroretinographic changes in aged pigeons.
pubmed:affiliation
Institute of Neurophysiology, CNR, Pisa, Italy.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.