rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2008-4-25
|
pubmed:abstractText |
Interphotoreceptor retinoid binding protein (IRBP) is the major uveitogenic retinal antigen eliciting experimental autoimmune uveoretinitis (EAU) in mice. The most frequently used mouse strains are B10.RIII and C57BL/6, but to date only one uveitogenic epitope for each has been identified. The purpose of this study was to identify and characterize additional uveitogenic epitopes in B10.RIII and C57BL/6 mice and to compare epitope recognition in wild-type versus IRBP-deficient mice on both backgrounds.
|
pubmed:grant |
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-10457585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-10634611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-10930316,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-14599843,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-14657219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-16585264,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-1703544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-1712808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-1748544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-1775528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-2200648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-2397018,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-2477180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-2786534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-2910846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-3346541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-3485569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-3487790,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-3967952,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-7516668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-7706044,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-7851121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-8318167,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-9317106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18436827-9614228
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0146-0404
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
49
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1946-56
|
pubmed:dateRevised |
2011-9-19
|
pubmed:meshHeading |
pubmed-meshheading:18436827-Amino Acid Sequence,
pubmed-meshheading:18436827-Animals,
pubmed-meshheading:18436827-Autoimmune Diseases,
pubmed-meshheading:18436827-CD4-CD8 Ratio,
pubmed-meshheading:18436827-CD4-Positive T-Lymphocytes,
pubmed-meshheading:18436827-CD8-Positive T-Lymphocytes,
pubmed-meshheading:18436827-Cytokines,
pubmed-meshheading:18436827-Eye Proteins,
pubmed-meshheading:18436827-Female,
pubmed-meshheading:18436827-H-2 Antigens,
pubmed-meshheading:18436827-Haplotypes,
pubmed-meshheading:18436827-Immunodominant Epitopes,
pubmed-meshheading:18436827-Lymphocyte Activation,
pubmed-meshheading:18436827-Male,
pubmed-meshheading:18436827-Mice,
pubmed-meshheading:18436827-Mice, Inbred C57BL,
pubmed-meshheading:18436827-Mice, Knockout,
pubmed-meshheading:18436827-Molecular Sequence Data,
pubmed-meshheading:18436827-Peptide Fragments,
pubmed-meshheading:18436827-Retinitis,
pubmed-meshheading:18436827-Retinol-Binding Proteins,
pubmed-meshheading:18436827-Uveitis
|
pubmed:year |
2008
|
pubmed:articleTitle |
Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice.
|
pubmed:affiliation |
Laboratory of Immunology, National Eye Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Intramural
|