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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-6-19
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pubmed:abstractText |
This study describes a new method for analyzing microcirculatory videos. It introduces algorithms for quantitative assessment of vessel length, diameter, the functional microcirculatory density distribution and red blood-cell (RBC) velocity in individual vessels as well as its distribution. The technique was validated and compared to commercial software. The method was applied to the sublingual microcirculation in a healthy volunteer and in a patient during cardiac surgery. Analysis time was reduced from hours to minutes compared to previous methods requiring manual vessel identification. Vessel diameter was detected with high accuracy (>80%, d > 3 pixels). Capillary length was estimated within 5 pixels accuracy. Velocity estimation was very accurate (>95%) in the range [2.5, 1,000] pixels/s. RBC velocity was reduced by 70% during the first 10 s of cardiac luxation. The present method has been shown to be fast and accurate and provides increased insight into the functional properties of the microcirculation.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-10720883,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-11408415,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-11728549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-11754431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-11867912,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-12091178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-12187127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-12423989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-1474928,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-15084075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-15087565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-15280096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-15343008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-15347769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-16147466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-16424721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-16525591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-16715034,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-3220679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18427850-7564793
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1741-0444
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
659-70
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18427850-Blood Flow Velocity,
pubmed-meshheading:18427850-Coronary Artery Bypass, Off-Pump,
pubmed-meshheading:18427850-Erythrocytes,
pubmed-meshheading:18427850-Humans,
pubmed-meshheading:18427850-Image Processing, Computer-Assisted,
pubmed-meshheading:18427850-Male,
pubmed-meshheading:18427850-Microcirculation,
pubmed-meshheading:18427850-Microscopy, Video,
pubmed-meshheading:18427850-Reproducibility of Results,
pubmed-meshheading:18427850-Software Design
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pubmed:year |
2008
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pubmed:articleTitle |
Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis.
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pubmed:affiliation |
Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. j.g.dobbe@amc.uva.nl
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pubmed:publicationType |
Journal Article,
Validation Studies
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