18425971

Source:http://linkedlifedata.com/resource/pubmed/id/18425971

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002144, umls-concept:C0021289, umls-concept:C0026538, umls-concept:C0026565, umls-concept:C0085584, umls-concept:C0750491, umls-concept:C1292733
pubmed:issue	2
pubmed:dateCreated	2008-4-21
pubmed:abstractText	Delayed neuronal death following a perinatal hypoxic insult is due partly to xanthine oxidase-mediated production of cytotoxic free radicals. Evidence exists that allopurinol, a xanthine-oxidase inhibitor, reduces delayed cell death in animal models of perinatal asphyxia and in human patients with other forms of organ reperfusion injury.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100909747
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Allopurinol, http://linkedlifedata.com/resource/pubmed/chemical/Free Radical Scavengers
pubmed:status	MEDLINE
pubmed:issn	1469-493X
pubmed:author	pubmed-author:ChaudhariTejasviT, pubmed-author:McGuireWilliamW
pubmed:issnType	Electronic
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	CD006817
pubmed:meshHeading	pubmed-meshheading:18425971-Allopurinol, pubmed-meshheading:18425971-Free Radical Scavengers, pubmed-meshheading:18425971-Humans, pubmed-meshheading:18425971-Hypoxia-Ischemia, Brain, pubmed-meshheading:18425971-Infant, Newborn, pubmed-meshheading:18425971-Randomized Controlled Trials as Topic
pubmed:year	2008
pubmed:articleTitle	Allopurinol for preventing mortality and morbidity in newborn infants with suspected hypoxic-ischaemic encephalopathy.
pubmed:affiliation	Centre for Newborn Care, Canberra Hospital, Canberra, ACT, Australia, 2605.
pubmed:publicationType	Journal Article, Review, Meta-Analysis