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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0032143,
umls-concept:C0034392,
umls-concept:C0086418,
umls-concept:C0127400,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0225336,
umls-concept:C1120843,
umls-concept:C1335858,
umls-concept:C2911684
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pubmed:issue |
6
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pubmed:dateCreated |
2008-5-20
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pubmed:abstractText |
Wine polyphenol quercetin upregulates tissue-type plasminogen activator (t-PA) transcription in cultured human umbilical cord vein endothelial cells (HUVECs). However, the regulatory elements and signaling pathways involved in this regulation are unknown.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
976-85
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18419748-Antioxidants,
pubmed-meshheading:18419748-Cells, Cultured,
pubmed-meshheading:18419748-Endothelium, Vascular,
pubmed-meshheading:18419748-Enzyme Inhibitors,
pubmed-meshheading:18419748-Flavonoids,
pubmed-meshheading:18419748-Gene Expression Regulation,
pubmed-meshheading:18419748-Humans,
pubmed-meshheading:18419748-Models, Biological,
pubmed-meshheading:18419748-Phenols,
pubmed-meshheading:18419748-Polyphenols,
pubmed-meshheading:18419748-Promoter Regions, Genetic,
pubmed-meshheading:18419748-Protein Binding,
pubmed-meshheading:18419748-Quercetin,
pubmed-meshheading:18419748-Sp1 Transcription Factor,
pubmed-meshheading:18419748-Thrombosis,
pubmed-meshheading:18419748-Up-Regulation,
pubmed-meshheading:18419748-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2008
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pubmed:articleTitle |
Quercetin induced tissue-type plasminogen activator expression is mediated through Sp1 and p38 mitogen-activated protein kinase in human endothelial cells.
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pubmed:affiliation |
The Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 34194-2170, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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