Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7193
pubmed:dateCreated
2008-5-15
pubmed:abstractText
We often face alternatives that we are free to choose between. Planning movements to select an alternative involves several areas in frontal and parietal cortex that are anatomically connected into long-range circuits. These areas must coordinate their activity to select a common movement goal, but how neural circuits make decisions remains poorly understood. Here we simultaneously record from the dorsal premotor area (PMd) in frontal cortex and the parietal reach region (PRR) in parietal cortex to investigate neural circuit mechanisms for decision making. We find that correlations in spike and local field potential (LFP) activity between these areas are greater when monkeys are freely making choices than when they are following instructions. We propose that a decision circuit featuring a sub-population of cells in frontal and parietal cortex may exchange information to coordinate activity between these areas. Cells participating in this decision circuit may influence movement choices by providing a common bias to the selection of movement goals.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-10421364, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-10746726, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-12134152, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-14963333, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-15205529, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-15748854, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-15848811, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16150631, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16192371, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16563737, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16571770, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16815337, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16971521, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-16988047, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-17014301, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-17314296, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-17395832, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-17546027, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-3653323, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-3880898, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-8232553, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-8670643, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-8985893, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-8987386, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-9056706, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-9395398, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-9636126, http://linkedlifedata.com/resource/pubmed/commentcorrection/18418380-9929474
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1476-4687
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
453
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
406-9
pubmed:dateRevised
2011-8-1
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Free choice activates a decision circuit between frontal and parietal cortex.
pubmed:affiliation
Center for Neural Science, New York University, New York, New York 10003, USA. bijan@nyu.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural