|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2008-5-29
|
|
pubmed:abstractText |
High-resolution melting is an emerging technique for detection of nucleic acid sequence variations. Developments in instrumentation and saturating intercalating dyes have made accurate high-resolution melting analysis possible and created opportunities to use this technology in diagnostic settings. We evaluated 2 high-resolution melting instruments for screening BRCA1 and BRCA2 mutations.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0009-9147
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
54
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
982-9
|
|
pubmed:dateRevised |
2010-11-18
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|
pubmed:meshHeading |
pubmed-meshheading:18403564-Apoptosis Regulatory Proteins,
pubmed-meshheading:18403564-BRCA1 Protein,
pubmed-meshheading:18403564-BRCA2 Protein,
pubmed-meshheading:18403564-Breast Neoplasms,
pubmed-meshheading:18403564-Disease Susceptibility,
pubmed-meshheading:18403564-Female,
pubmed-meshheading:18403564-Humans,
pubmed-meshheading:18403564-Mutation,
pubmed-meshheading:18403564-Polymerase Chain Reaction,
pubmed-meshheading:18403564-Sensitivity and Specificity,
pubmed-meshheading:18403564-Transition Temperature
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Rapid and sensitive detection of BRCA1/2 mutations in a diagnostic setting: comparison of two high-resolution melting platforms.
|
|
pubmed:affiliation |
Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
