Source:http://linkedlifedata.com/resource/pubmed/id/18401060
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2008-4-18
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pubmed:abstractText |
In proton scanning systems that employ active energy variation for depth modulation, a switch of the particle energy might typically require 1-2 s. For plans comprising many energy slices, these seconds could sum up to a non-negligible fraction of the total treatment duration. We have applied the Nyquist-Shannon sampling theorem to determine an efficient spatial arrangement of Bragg peaks in a target volume. This pre-determined schedule of increasing energy spacing with higher energy allows us to reduce the number of used energy slices without compromising the physical dosimetric quality of a plan. Our results suggest that the advantage of such a simple implementation would be especially significant for larger, deep-seated tumors such as the prostate; the number of energy slices was cut by a factor of 2-6.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0031-9155
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
N149-55
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pubmed:meshHeading |
pubmed-meshheading:18401060-Automation,
pubmed-meshheading:18401060-Equipment Design,
pubmed-meshheading:18401060-Humans,
pubmed-meshheading:18401060-Male,
pubmed-meshheading:18401060-Models, Theoretical,
pubmed-meshheading:18401060-Normal Distribution,
pubmed-meshheading:18401060-Prostatic Neoplasms,
pubmed-meshheading:18401060-Protons,
pubmed-meshheading:18401060-Radiation Oncology,
pubmed-meshheading:18401060-Radiometry,
pubmed-meshheading:18401060-Radiotherapy Dosage,
pubmed-meshheading:18401060-Radiotherapy Planning, Computer-Assisted,
pubmed-meshheading:18401060-Software,
pubmed-meshheading:18401060-Time Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Non-uniform depth scanning for proton therapy systems employing active energy variation.
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pubmed:affiliation |
Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. j.kang@dkfz.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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