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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-4-8
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pubmed:abstractText |
K(+) recycling at the apical membrane of gastric parietal cells is a prerequisite for gastric acid secretion. Two K(+) channels are currently being considered for this function, namely KCNQ1 and inwardly rectifying K(+) channels (Kir). This study addresses the subcellular localization, trafficking, and potential functional significance of KCNQ1 and Kir4.1 channels during stimulated acid secretion.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:BeilWinfriedW,
pubmed-author:EngelhardtReginaR,
pubmed-author:FährmannMichaelM,
pubmed-author:HagenSusan JSJ,
pubmed-author:KaufholdMarc-AndréMA,
pubmed-author:KlöckerNikolajN,
pubmed-author:KrabbenhöftAnjaA,
pubmed-author:MannsMichaelM,
pubmed-author:RiedererBrigitteB,
pubmed-author:SeidlerUrsulaU,
pubmed-author:SongPenghongP
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pubmed:issnType |
Electronic
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1058-69
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pubmed:meshHeading |
pubmed-meshheading:18395087-Animals,
pubmed-meshheading:18395087-Blotting, Western,
pubmed-meshheading:18395087-Cells, Cultured,
pubmed-meshheading:18395087-Chromans,
pubmed-meshheading:18395087-Disease Models, Animal,
pubmed-meshheading:18395087-Gastric Acid,
pubmed-meshheading:18395087-H(+)-K(+)-Exchanging ATPase,
pubmed-meshheading:18395087-Immunohistochemistry,
pubmed-meshheading:18395087-Immunoprecipitation,
pubmed-meshheading:18395087-KCNQ1 Potassium Channel,
pubmed-meshheading:18395087-Male,
pubmed-meshheading:18395087-Mice,
pubmed-meshheading:18395087-Microscopy, Confocal,
pubmed-meshheading:18395087-Parietal Cells, Gastric,
pubmed-meshheading:18395087-Potassium Channels, Inwardly Rectifying,
pubmed-meshheading:18395087-Rabbits,
pubmed-meshheading:18395087-Rats,
pubmed-meshheading:18395087-Rats, Wistar,
pubmed-meshheading:18395087-Sodium-Potassium-Exchanging ATPase,
pubmed-meshheading:18395087-Sulfonamides
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pubmed:year |
2008
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pubmed:articleTitle |
Localization, trafficking, and significance for acid secretion of parietal cell Kir4.1 and KCNQ1 K+ channels.
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pubmed:affiliation |
Department of Gastroenterology, Hannover Medical School, Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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