Source:http://linkedlifedata.com/resource/pubmed/id/18383729
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-4-3
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pubmed:abstractText |
Influence of synthetic fragment 65-76 of monocyte chemoattractant protein-1 (MCP-1) (peptide X) on development of neointima after balloon injury of carotid artery was investigated. Peptide X was introduced intramuscularly, 33 pg/kg, daily during 28 days after balloon injury. In days 4 and 7 after intervention, in animals receiving peptide X in comparison with control animals a substantial decrease of neointimal growth was observed. On 14 and 28 days there, was no significant difference in neointima development in rats with and without peptide treatment. Injections of peptide X did not after the C-reactive protein concentration, leukocyte number and lymphocyte subpopulations in peripheral blood. Peptide X treatment along with traditional therapy may be effective in preventing restenosis after angioplasty.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0869-8139
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-36
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pubmed:meshHeading |
pubmed-meshheading:18383729-Animals,
pubmed-meshheading:18383729-C-Reactive Protein,
pubmed-meshheading:18383729-Carotid Arteries,
pubmed-meshheading:18383729-Carotid Artery Injuries,
pubmed-meshheading:18383729-Chemokine CCL2,
pubmed-meshheading:18383729-Graft Occlusion, Vascular,
pubmed-meshheading:18383729-Leukocyte Count,
pubmed-meshheading:18383729-Male,
pubmed-meshheading:18383729-Peptides,
pubmed-meshheading:18383729-Rats,
pubmed-meshheading:18383729-Rats, Wistar,
pubmed-meshheading:18383729-Tunica Intima
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pubmed:year |
2008
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pubmed:articleTitle |
[The effect of synthetic fragment 65-76 of monocyte chemiattractant protein-1 (MCP-1) on neointima growth after carotid artery balloon injury in rats].
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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