Linked Life Data

18379532

Source:http://linkedlifedata.com/resource/pubmed/id/18379532

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
108
pubmed:dateCreated
2008-4-1
pubmed:abstractText
The achievement of euvolemia is essential to the successful management of peritoneal dialysis patients. However, the concern that hypertonic glucose exchanges may have a role in long-term changes to the peritoneal membrane has lead to an alternative strategy to enhance ultrafiltration (UF) over the long dwell by combining crystalloid and colloid osmosis. This review summarizes the experience of mixing glucose or amino acids with polyglucose (icodextrin), with particular focus given to data from studies using glucose/icodextrin in combinations of 1.36%/7.5% and 2.61%/6.8%. Both combinations demonstrate a significant increment of UF volume and sodium removal compared with the component osmotic agents used individually over long dwells, with the 2.61%/6.8% mixture having an effect over dwells extending to 15 h. Hypothetically, the mechanism of the enhanced UF is the attenuation by the colloid osmotic force of the backflow of water through small pores from dialysate to the peritoneal capillary circulation once the crystalloid osmotic force has dissipated. This experience provides promising data that deserves further examination in longer term clinical studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0098-6577
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S102-11
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The contribution of combined crystalloid and colloid osmosis to fluid and sodium management in peritoneal dialysis.
pubmed:affiliation
Department of Nephrology and Dialysis Center, Louis Pasteur Hospital, Cherbourg, France. p.freida@ch-cherbourg.fr
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't