Source:http://linkedlifedata.com/resource/pubmed/id/18375772
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-3-31
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pubmed:abstractText |
Strong evidence exists demonstrating the benefits of tight glycemic control in type 1 and type 2 diabetes mellitus patients, but glycemic goals are not adequately achieved for many patients. Advancement in the knowledge surrounding the physiology of endogenous glucoregulatory peptide hormones, such as glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1, has led to new therapeutic targets for the treatment of type 2 diabetes mellitus. Dipeptidyl peptidase-4 (DPP-4) inhibitors provide practitioners with a novel mechanism of action to use for combination therapies for the treatment of type 2 diabetes mellitus. This article, part 3 of a 3-part series, reviews the new class of medications known as DPP-4 inhibitors as well as discusses a future buccal insulin formulation, Oral-Lyn, on the horizon for the treatment of diabetes mellitus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
N
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DPP4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Dipeptidyl Peptidase 4,
http://linkedlifedata.com/resource/pubmed/chemical/Dipeptidyl-Peptidase IV Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazines,
http://linkedlifedata.com/resource/pubmed/chemical/Triazoles,
http://linkedlifedata.com/resource/pubmed/chemical/sitagliptin
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pubmed:status |
MEDLINE
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pubmed:issn |
0145-7217
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183-200
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18375772-Diabetes Mellitus, Type 2,
pubmed-meshheading:18375772-Dipeptidyl Peptidase 4,
pubmed-meshheading:18375772-Dipeptidyl-Peptidase IV Inhibitors,
pubmed-meshheading:18375772-Humans,
pubmed-meshheading:18375772-Hypoglycemic Agents,
pubmed-meshheading:18375772-Pyrazines,
pubmed-meshheading:18375772-Triazoles
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pubmed:articleTitle |
Looking to the future: focus on DPP-4 inhibitors for the treatment of type 2 diabetes and emerging therapies.
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pubmed:affiliation |
PharmD, Department of Pharmacotherapy, College of Pharmacy, Washington State University/Elder Services, 5125 North Market Street, Spokane, WA 99217, USA. jneumiller@wsu.edu
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pubmed:publicationType |
Journal Article
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