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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-12-1
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pubmed:abstractText |
Prostate cancer is a major cause of cancer mortality in American males. Once prostate cancer has metastasized, there is currently no curative therapy available. The development of effective agents is therefore a continuing effort to combat this disease. In the present study, the effects and potential mechanisms of NSC606985 (NSC), a water-soluble camptothecin analog, in prostate cancer cells were investigated.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1432-0843
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
303-12
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pubmed:meshHeading |
pubmed-meshheading:18373093-Antineoplastic Agents,
pubmed-meshheading:18373093-Apoptosis,
pubmed-meshheading:18373093-Blotting, Western,
pubmed-meshheading:18373093-Camptothecin,
pubmed-meshheading:18373093-Caspase 3,
pubmed-meshheading:18373093-Caspase 7,
pubmed-meshheading:18373093-Cell Line, Tumor,
pubmed-meshheading:18373093-Cell Proliferation,
pubmed-meshheading:18373093-Cytochromes c,
pubmed-meshheading:18373093-DNA Fragmentation,
pubmed-meshheading:18373093-Flow Cytometry,
pubmed-meshheading:18373093-Humans,
pubmed-meshheading:18373093-Male,
pubmed-meshheading:18373093-Prostatic Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells.
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pubmed:affiliation |
Department of Medicine/Endocrinology, Weill Medical College of Cornell University, 1300 York Avenue, Box-149, Room F-233, New York, NY 10021, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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