Linked Life Data

18367608

Source:http://linkedlifedata.com/resource/pubmed/id/18367608

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2008-3-27
pubmed:abstractText
A fundamental feature of auditory perception is the constancy of sound recognition over a large range of intensities. Although this invariance has been described in behavioral studies, the underlying neural mechanism is essentially unknown. Here we show a putative level-invariant representation of sounds by populations of neurons in primary auditory cortex (A1) that may provide a neural basis for the behavioral observations. Previous studies reported that pure-tone frequency tuning of most A1 neurons widens with increasing sound level. In sharp contrast, we found that a large proportion of neurons in A1 of awake marmosets were narrowly and separably tuned to both frequency and sound level. Tuning characteristics and firing rates of the neural population were preserved across all tested sound levels. These response properties lead to a level-invariant representation of sounds over the population of A1 neurons. Such a representation is an important step for robust feature recognition in natural environments.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
26
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3415-26
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Level invariant representation of sounds by populations of neurons in primary auditory cortex.
pubmed:affiliation
Laboratory of Auditory Neurophysiology, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. vatsun@jhu.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural