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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-4-25
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pubmed:abstractText |
Disruption of mitochondrial genes may become a powerful tool for elucidating precisely the functions of individual mitochondrial genes. However, it is generally difficult to manipulate genetically mitochondrial genes, because 1) a mitochondrion is surrounded by inner and outer membranes, and 2) there are a large number of mtDNA copies in a single cell. This is the reason why we tried to establish a novel method for disrupting a certain mitochondrial gene (rps4), using Dictyostelium cells.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-10570466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-10821186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-10903439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-11193053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-12372991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-12467494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-15226392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-16157183,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-16179392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-2541333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-3192850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-3600419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-9461442,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18366713-9572147
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2156
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18366713-Animals,
pubmed-meshheading:18366713-Blotting, Northern,
pubmed-meshheading:18366713-Blotting, Southern,
pubmed-meshheading:18366713-DNA, Mitochondrial,
pubmed-meshheading:18366713-Dictyostelium,
pubmed-meshheading:18366713-Gene Targeting,
pubmed-meshheading:18366713-Genes, Mitochondrial,
pubmed-meshheading:18366713-Genes, Protozoan,
pubmed-meshheading:18366713-Phenotype,
pubmed-meshheading:18366713-Ribosomal Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Establishment of a new method for precisely determining the functions of individual mitochondrial genes, using Dictyostelium cells.
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pubmed:affiliation |
Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Aoba, Sendai 980-8578, Japan. j-chida@ier.tokushima-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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