Source:http://linkedlifedata.com/resource/pubmed/id/18364438
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2008-7-16
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pubmed:abstractText |
The mismatch repair (MMR) genes are in charge of maintaining genomic integrity. Mutations in the MMR genes are at the origin of a familial form of colorectal cancer (CRC). This syndrome accounts for only a small proportion of the excess familial risk of CRC. The characteristics of the alleles that account for the remainder of cases are unknown. To assess the putative associations between common variants in MMR genes and CRC, we performed a genetic case-control study using a single-nucleotide polymorphism (SNP) tagging approach.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1468-3288
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1097-101
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pubmed:meshHeading |
pubmed-meshheading:18364438-Adolescent,
pubmed-meshheading:18364438-Adult,
pubmed-meshheading:18364438-Aged,
pubmed-meshheading:18364438-Case-Control Studies,
pubmed-meshheading:18364438-Colorectal Neoplasms,
pubmed-meshheading:18364438-DNA Mismatch Repair,
pubmed-meshheading:18364438-Female,
pubmed-meshheading:18364438-Gene Frequency,
pubmed-meshheading:18364438-Genetic Predisposition to Disease,
pubmed-meshheading:18364438-Genotype,
pubmed-meshheading:18364438-Haplotypes,
pubmed-meshheading:18364438-Humans,
pubmed-meshheading:18364438-Male,
pubmed-meshheading:18364438-Middle Aged,
pubmed-meshheading:18364438-Polymorphism, Single Nucleotide
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pubmed:year |
2008
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pubmed:articleTitle |
Common variants in mismatch repair genes and risk of colorectal cancer.
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pubmed:affiliation |
Cancer Research UK Department of Oncology, Strangeways Research Laboratory, University of Cambridge, Worts Causeway, Cambridge, UK. Thibaud@srl.cam.ac.uk
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pubmed:publicationType |
Journal Article
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