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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-3-24
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pubmed:abstractText |
Time-course and concentration-effect experiments with multiple time-points and drug concentrations provide far more valuable information than experiments with just two design-points (treated vs. control), as commonly performed in most microarray studies. Analysis of the data from such complex experiments, however, remains a challenge.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1109-6535
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-53
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pubmed:meshHeading |
pubmed-meshheading:18359979-Antineoplastic Agents,
pubmed-meshheading:18359979-Cell Line, Tumor,
pubmed-meshheading:18359979-Cisplatin,
pubmed-meshheading:18359979-Dose-Response Relationship, Drug,
pubmed-meshheading:18359979-Gene Expression,
pubmed-meshheading:18359979-Gene Expression Profiling,
pubmed-meshheading:18359979-Genes, Neoplasm,
pubmed-meshheading:18359979-Humans,
pubmed-meshheading:18359979-Kinetics,
pubmed-meshheading:18359979-Models, Statistical,
pubmed-meshheading:18359979-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18359979-Organoplatinum Compounds,
pubmed-meshheading:18359979-Regression Analysis
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pubmed:articleTitle |
Simultaneous modeling of concentration-effect and time-course patterns in gene expression data from microarrays.
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pubmed:affiliation |
Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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