|
rdf:type |
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lifeskim:mentions |
umls-concept:C0003593,
umls-concept:C0007382,
umls-concept:C0013203,
umls-concept:C0014507,
umls-concept:C0019704,
umls-concept:C0205202,
umls-concept:C0242781,
umls-concept:C0449432,
umls-concept:C0733511,
umls-concept:C0868955,
umls-concept:C1179435,
umls-concept:C1519249,
umls-concept:C1521797,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2008-3-21
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|
pubmed:abstractText |
Promiscuous guanine (G) to adenine (A) substitutions catalysed by apolipoprotein B RNA-editing catalytic component (APOBEC) enzymes are observed in a proportion of HIV-1 sequences in vivo and can introduce artifacts into some genetic analyses. The potential impact of undetected lethal editing on genotypic estimation of transmitted drug resistance was assessed.
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pubmed:grant |
|
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pubmed:commentsCorrections |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1473-5571
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:day |
30
|
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pubmed:volume |
22
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
717-25
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:18356601-Base Sequence,
pubmed-meshheading:18356601-Cytidine Deaminase,
pubmed-meshheading:18356601-Databases, Genetic,
pubmed-meshheading:18356601-Developing Countries,
pubmed-meshheading:18356601-Drug Resistance, Multiple, Viral,
pubmed-meshheading:18356601-Genes, MDR,
pubmed-meshheading:18356601-Genes, Viral,
pubmed-meshheading:18356601-Genotype,
pubmed-meshheading:18356601-HIV Infections,
pubmed-meshheading:18356601-HIV Protease,
pubmed-meshheading:18356601-HIV Reverse Transcriptase,
pubmed-meshheading:18356601-HIV-1,
pubmed-meshheading:18356601-Humans,
pubmed-meshheading:18356601-Molecular Sequence Data,
pubmed-meshheading:18356601-RNA Editing,
pubmed-meshheading:18356601-ROC Curve,
pubmed-meshheading:18356601-Sequence Analysis, DNA
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
Sequence editing by Apolipoprotein B RNA-editing catalytic component [corrected] and epidemiological surveillance of transmitted HIV-1 drug resistance.
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pubmed:affiliation |
Division of Infectious Diseases, Department of Medicine, Stanford University, Stanford, California 94305, USA. rjmg@stanford.edu
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pubmed:publicationType |
Journal Article
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