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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-4-29
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pubmed:abstractText |
Circulating lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) has emerged as a novel biomarker for cardiovascular diseases. However, the correlation between the plaque expression of Lp-PLA(2) and plaque oxidative stress, inflammation, and stability as well as the clinical presentation remains poorly defined, especially for cerebrovascular disease. Therefore, this study was performed to test the hypothesis that Lp-PLA(2) expression is higher in symptomatic than in asymptomatic carotid plaques of patients undergoing carotid endarterectomy.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4628
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1448-55
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pubmed:meshHeading |
pubmed-meshheading:18356547-1-Alkyl-2-acetylglycerophosphocholine Esterase,
pubmed-meshheading:18356547-Aged,
pubmed-meshheading:18356547-Biological Markers,
pubmed-meshheading:18356547-Carotid Arteries,
pubmed-meshheading:18356547-Carotid Artery Diseases,
pubmed-meshheading:18356547-Collagen,
pubmed-meshheading:18356547-Endarterectomy, Carotid,
pubmed-meshheading:18356547-Female,
pubmed-meshheading:18356547-Humans,
pubmed-meshheading:18356547-Immunoblotting,
pubmed-meshheading:18356547-Immunohistochemistry,
pubmed-meshheading:18356547-Inflammation,
pubmed-meshheading:18356547-Lipoproteins, LDL,
pubmed-meshheading:18356547-Lysophosphatidylcholines,
pubmed-meshheading:18356547-Macrophages,
pubmed-meshheading:18356547-Male,
pubmed-meshheading:18356547-Oxidative Stress,
pubmed-meshheading:18356547-Predictive Value of Tests,
pubmed-meshheading:18356547-Up-Regulation
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pubmed:year |
2008
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pubmed:articleTitle |
Enhanced expression of Lp-PLA2 and lysophosphatidylcholine in symptomatic carotid atherosclerotic plaques.
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pubmed:affiliation |
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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