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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1992-1-9
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pubmed:abstractText |
25 previously untreated patients with inoperable or metastatic adenocarcinoma of the oesophagus or oesophageal-gastric junction area were treated with ifosfamide 6 g/m2 over 48 hours, combined with mesna 6 g/m2. 1 complete response and 1 partial response were seen among 23 patients evaluable, with a response duration of 29+ months and 7 months, respectively. Toxicity was not severe: grade 3 infection in 2 patients, grade 3 leucopenia in 3 patients and grade 3 nausea in 4 patients. No life-threatening episodes or central nervous system toxicity were encountered. Ifosfamide has limited activity in adenocarcinoma of the oesophageal-gastric junction area.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0959-8049
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1112-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1835618-Adenocarcinoma,
pubmed-meshheading:1835618-Adult,
pubmed-meshheading:1835618-Aged,
pubmed-meshheading:1835618-Esophageal Neoplasms,
pubmed-meshheading:1835618-Esophagogastric Junction,
pubmed-meshheading:1835618-Female,
pubmed-meshheading:1835618-Humans,
pubmed-meshheading:1835618-Ifosfamide,
pubmed-meshheading:1835618-Male,
pubmed-meshheading:1835618-Middle Aged,
pubmed-meshheading:1835618-Neoplasm Metastasis,
pubmed-meshheading:1835618-Prognosis,
pubmed-meshheading:1835618-Treatment Refusal
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pubmed:year |
1991
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pubmed:articleTitle |
Ifosfamide in advanced adenocarcinoma of the oesophagus or oesophageal-gastric junction area. Rotterdam Esophageal Tumor Study Group.
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pubmed:affiliation |
Department of Medical Oncology, University Hospital Rotterdam, The Netherlands.
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pubmed:publicationType |
Journal Article
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