A novel enzyme, named RimO for ribosomal modification (Anton et al., 2008) catalyzes the methylthiolation of aspartate 88 of the S12 ribosomal protein in Escherichia coli and shows a strong similarity with the iron-sulfur enzyme MiaB involved in the methylthiolation of tRNAs.
Laboratoire de Chimie et Biologie des Métaux, UMR 5249, Université Joseph Fourier, CEA, CNRS, 17 Avenue des Martyrs, 38054 Grenoble Cedex 9, France. M.Fontecave.mfontecave@cea.fr