Source:http://linkedlifedata.com/resource/pubmed/id/18345641
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-4-25
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pubmed:abstractText |
A pentacyclic ent-kauranoid, nervonin A ( 1), with an unprecedented cyclobutane moiety in the structure, and nine other new ent-kaurane diterpenoids, nervonins B-J ( 2- 10), along with 10 known ones ( 11- 20), were isolated from Isodon nervosus. Their structures were elucidated by detailed spectroscopic analysis. All diterpenoids were assayed for their cytotoxicity against K562, A549, and HepG2 human cell lines. Compounds 2, 11, 16, 17, and 20 showed significant cytotoxicity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
684-8
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pubmed:meshHeading |
pubmed-meshheading:18345641-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:18345641-Diterpenes,
pubmed-meshheading:18345641-Diterpenes, Kaurane,
pubmed-meshheading:18345641-Drug Screening Assays, Antitumor,
pubmed-meshheading:18345641-Drugs, Chinese Herbal,
pubmed-meshheading:18345641-Humans,
pubmed-meshheading:18345641-Isodon,
pubmed-meshheading:18345641-K562 Cells,
pubmed-meshheading:18345641-Molecular Structure,
pubmed-meshheading:18345641-Plants, Medicinal
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pubmed:year |
2008
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pubmed:articleTitle |
ent-Kaurane Diterpenoids from Isodon nervosus.
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pubmed:affiliation |
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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