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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-13
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pubmed:abstractText |
Monitoring of the area under the plasma concentration-time curve (AUC) of mycophenolic acid (MPA) has been developed for individual dose adjustment of mycophenolate mofetil (MMF) in renal allograft recipients. MMF is currently used as an off-label drug in the treatment of systemic lupus erythematosus (SLE), but factors of its exposition may be different in these patients and need to be determined for therapeutic drug monitoring (TDM) purposes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0312-5963
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
277-84
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pubmed:meshHeading |
pubmed-meshheading:18336056-Administration, Oral,
pubmed-meshheading:18336056-Adolescent,
pubmed-meshheading:18336056-Adult,
pubmed-meshheading:18336056-Aged,
pubmed-meshheading:18336056-Area Under Curve,
pubmed-meshheading:18336056-Bayes Theorem,
pubmed-meshheading:18336056-Chromatography, High Pressure Liquid,
pubmed-meshheading:18336056-Dose-Response Relationship, Drug,
pubmed-meshheading:18336056-Drug Monitoring,
pubmed-meshheading:18336056-Female,
pubmed-meshheading:18336056-Humans,
pubmed-meshheading:18336056-Immunosuppressive Agents,
pubmed-meshheading:18336056-Lupus Erythematosus, Systemic,
pubmed-meshheading:18336056-Male,
pubmed-meshheading:18336056-Middle Aged,
pubmed-meshheading:18336056-Models, Biological,
pubmed-meshheading:18336056-Mycophenolic Acid,
pubmed-meshheading:18336056-Time Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Pharmacokinetic study of mycophenolate mofetil in patients with systemic lupus erythematosus and design of Bayesian estimator using limited sampling strategies.
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pubmed:affiliation |
Department of Pharmacology, Pitié-Salpêtrière Hospital, Faculté Pierre et Marie Curie, Paris VI, Assistance Publique Hôpitaux de Paris, Paris, France. noel.zahr@psl.aphp.fr
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pubmed:publicationType |
Journal Article,
Clinical Trial
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