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rdf:type |
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lifeskim:mentions |
umls-concept:C0004561,
umls-concept:C0017262,
umls-concept:C0020846,
umls-concept:C0026691,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0229664,
umls-concept:C0229671,
umls-concept:C0439098,
umls-concept:C0441889,
umls-concept:C1414549,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
1991-11-4
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pubmed:abstractText |
We analyzed the expression of Fc epsilon R2/CD23 on the peripheral blood B lymphocytes of 10 patients with Kawasaki disease (KD) using a fluorescence-activated cell sorter. The absolute count of CD23-positive B lymphocytes and the ratio of CD23-positive B lymphocytes to B lymphocytes were high during the acute stage of KD in comparison to those during the convalescent stage and in control subjects. In addition, both the increased number of CD23-positive B lymphocytes and the increased serum IgE levels appeared during the latter part of the acute stage. These results suggest that the increased number of CD23-positive B lymphocytes during the latter part of the acute stage in KD reflect the activation of B lymphocytes and have an important role in IgE-mediated immunity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fc,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, IgE
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pubmed:status |
MEDLINE
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pubmed:issn |
0020-5915
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1833342-Antibodies, Monoclonal,
pubmed-meshheading:1833342-Antigens, CD,
pubmed-meshheading:1833342-Antigens, Differentiation, B-Lymphocyte,
pubmed-meshheading:1833342-B-Lymphocytes,
pubmed-meshheading:1833342-Cell Separation,
pubmed-meshheading:1833342-Child,
pubmed-meshheading:1833342-Child, Preschool,
pubmed-meshheading:1833342-Convalescence,
pubmed-meshheading:1833342-Female,
pubmed-meshheading:1833342-Flow Cytometry,
pubmed-meshheading:1833342-Humans,
pubmed-meshheading:1833342-Immunoenzyme Techniques,
pubmed-meshheading:1833342-Immunoglobulin E,
pubmed-meshheading:1833342-Infant,
pubmed-meshheading:1833342-Leukocyte Count,
pubmed-meshheading:1833342-Lymphocyte Activation,
pubmed-meshheading:1833342-Male,
pubmed-meshheading:1833342-Mucocutaneous Lymph Node Syndrome,
pubmed-meshheading:1833342-Receptors, Fc,
pubmed-meshheading:1833342-Receptors, IgE
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pubmed:year |
1991
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pubmed:articleTitle |
Increased expression of Fc epsilon R2/CD23 on peripheral blood B lymphocytes and serum IgE levels in Kawasaki disease.
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pubmed:affiliation |
Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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