Source:http://linkedlifedata.com/resource/pubmed/id/18315788
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-3-4
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pubmed:abstractText |
We present a series of cases of phenytoin toxicity where the diagnosis was initially missed. These patients all suffered unnecessary morbidity or investigations. The side-effects and unusual pharmacokinetics of phenytoin are discussed, as well as the array of potential drug interactions. We remind clinicians that phenytoin toxicity can easily mimic a cerebellar lesion or alcohol intoxication, and suggest that in accordance with National Institute for Clinical Excellence (NICE) guidelines phenytoin should no longer be used as a first-line treatment for epilepsy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2710
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
211-4
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pubmed:dateRevised |
2008-5-28
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pubmed:meshHeading |
pubmed-meshheading:18315788-Aged,
pubmed-meshheading:18315788-Anticonvulsants,
pubmed-meshheading:18315788-Cerebellar Diseases,
pubmed-meshheading:18315788-Epilepsy,
pubmed-meshheading:18315788-Humans,
pubmed-meshheading:18315788-Male,
pubmed-meshheading:18315788-Middle Aged,
pubmed-meshheading:18315788-Phenytoin
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pubmed:year |
2008
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pubmed:articleTitle |
Phenytoin toxicity: an easily missed cause of cerebellar syndrome.
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pubmed:affiliation |
Department of Elderly Care, Central Middlesex Hospital, London, UK. joshbrostoff@doctors.org.uk
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pubmed:publicationType |
Journal Article,
Case Reports
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