Source:http://linkedlifedata.com/resource/pubmed/id/18310793
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-3-3
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pubmed:abstractText |
The clinical profile and outcome of neuroblastoma in 103 children, older than one-year is presented. 74 had Stage IV, 27 Stage III and one patient each had Stage I or II disease. Treatment included chemotherapy followed by surgical resection/debulking. Radiotherapy was administered to those with residual tumor. Chemotherapy consisted of OPEC (vincristine, cyclophosphamide, cisplatin and etoposide). The caretakers of 54 (52.4%) children either did not opt for or defaulted therapy, whilst 3 patients died before chemotherapy could be initiated. Of the remaining 46 patients, the tumor progressed during therapy in 19 (41.3%). Relapse of disease was documented in 22 (47.8%) cases. Merely 4 (8.7%) children are disease free for a period of 16.5+/-6.7 months. Majority of children presented with advanced disease and the outcome was dismal with conventional non-myloablative chemotherapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0019-6061
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-9
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pubmed:meshHeading |
pubmed-meshheading:18310793-Adolescent,
pubmed-meshheading:18310793-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18310793-Brain Neoplasms,
pubmed-meshheading:18310793-Child,
pubmed-meshheading:18310793-Child, Preschool,
pubmed-meshheading:18310793-Female,
pubmed-meshheading:18310793-Humans,
pubmed-meshheading:18310793-Infant,
pubmed-meshheading:18310793-Male,
pubmed-meshheading:18310793-Neoplasm Recurrence, Local,
pubmed-meshheading:18310793-Neoplasm Staging,
pubmed-meshheading:18310793-Neuroblastoma
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pubmed:year |
2008
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pubmed:articleTitle |
Profile and outcome of neuroblastoma with convertional chemotherapy in children older than one year: a 15-years experience.
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pubmed:affiliation |
Pediatric Hematology/Oncology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
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pubmed:publicationType |
Journal Article
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