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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-4-23
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pubmed:abstractText |
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Ibuprofen is a nonsteroidal anti-inflammatory agent that induces closure of the patent ductus arteriosus in neonates. Few studies of ibuprofen pharmacokinetics have been performed and were limited to small groups of preterm infants, showing a large intersubject variability and an increase in clearance with either postnatal or gestational age.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1365-2125
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
629-36
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pubmed:dateRevised |
2011-1-11
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pubmed:meshHeading |
pubmed-meshheading:18307541-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:18307541-Area Under Curve,
pubmed-meshheading:18307541-Ductus Arteriosus, Patent,
pubmed-meshheading:18307541-Humans,
pubmed-meshheading:18307541-Ibuprofen,
pubmed-meshheading:18307541-Infant, Newborn,
pubmed-meshheading:18307541-Infant, Premature,
pubmed-meshheading:18307541-Infant, Very Low Birth Weight,
pubmed-meshheading:18307541-Infusions, Intravenous,
pubmed-meshheading:18307541-Logistic Models,
pubmed-meshheading:18307541-Lysine,
pubmed-meshheading:18307541-Respiratory Distress Syndrome, Newborn
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pubmed:year |
2008
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pubmed:articleTitle |
An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study.
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pubmed:affiliation |
EA3620, Université Paris - Descartes, Paris, France. deborah.hirt@univ-paris5.fr
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pubmed:publicationType |
Journal Article,
Multicenter Study
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