Linked Life Data

18307121

Source:http://linkedlifedata.com/resource/pubmed/id/18307121

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-2-29
pubmed:abstractText
Several strategies have been developed to treat atelectasis, including positive end-expiratory pressure and deep inspirations. However, in some patients these recruitment strategies fail to improve lung function. Therefore, the authors studied whether recruitment maneuvers could resolve atelectasis following either passive airway closure or active bronchconstriction. Aerated lung areas were measured in 5 dogs at baseline, and after airway closure with either a bronchial blocker, or administration of methacholine, followed by deep inspiration. Finally, bronchoconstriction was reversed pharmacologically. Bronchial occlusion reduced aerated lung areas, which were reopened by deep inspirations. Following methacholine, aerated lung areas were also significantly reduced; however, deep inspirations had no significant effect. Passive atelectasis was easily resolved by deep inspirations. In contrast, active airway constriction that leads to atelectasis could not be overcome with recruitment maneuvers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0190-2148
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
115-24
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Different mechanisms of atelectasis formation require different treatment strategies.
pubmed:affiliation
Department of Environmental Health Sciences/Division of Physiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA. harald.groeben@uni-essen.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't