Linked Life Data

18287557

Source:http://linkedlifedata.com/resource/pubmed/id/18287557

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-4-29
pubmed:abstractText
Reviewing the current picture of uremic toxicity reveals its complexity. Focusing on cardiovascular damage as a model of uremic effects resulting in substantial morbidity and mortality, most molecules with potential to affect the function of a variety of cell types within the vascular system are difficult to remove by dialysis. Examples are the larger middle molecular weight molecules and protein-bound molecules. Recent clinical studies suggest that enhancing the removal of these compounds is beneficial for survival. Future therapeutic options are discussed, including improved removal of toxins and the search for pharmacologic strategies blocking responsible pathophysiologic pathways.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1533-3450
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
863-70
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
A bench to bedside view of uremic toxins.
pubmed:affiliation
Nephrology Section, Department of Internal Medicine, OK12, University Hospital, De Pintelaan 185, B9000 Gent, Belgium. raymond.vanholder@ugent.be
pubmed:publicationType
Journal Article, Review