Linked Life Data

1824924

Source:http://linkedlifedata.com/resource/pubmed/id/1824924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1991-2-28
pubmed:abstractText
Transformation of NIH 3T3 cells with c-H-ras has been demonstrated to result in significantly increased activation of 5'-deoxy-5-fluorouridine and significantly increased cytotoxicity in vitro as compared to non-transformed NIH 3T3. FUra cytotoxicity appeared to be increased also in vitro upon transformation; the level of significance however was beyond that of accepted significance (0.05 less than P less than 0.01). Furthermore dFUrd proved to be less active in vivo in nude mice bearing v-fos transformed NIH 3T3 cells than in nude mice bearing c-H-ras transformed cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-2952
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
301-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Activation and cytotoxicity of 5'-deoxy-5-fluorouridine in c-H-ras transformed NIH 3T3 cells.
pubmed:affiliation
Laboratory of Cancer Research & Clinical Oncology, University of Antwerp, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't