Linked Life Data

18196639

Source:http://linkedlifedata.com/resource/pubmed/id/18196639

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-1-15
pubmed:abstractText
Therapeutics and clinical pharmacology of pediatric age had a turbulent development ever since H. Shirkey spelled out his dramatic warning in 1968. that children are "therapeutic orphans". This warning was a message that in children drugs are used which are not scientifically studied in this population. With a few years of latency in which the ethical issues have been solved. Food and Drug Administration and other leading drug regulatory authorities requested that in the drug labeling a warning sentence should be included stating that since the drug was not studied in children, its use is not recommended. Thus, the children became therapeutic orphans for the second time. Today, the attitude is prevailing that is based on pharmacokinetic and safety data so that even before the formal studies have been completed for each age group, use of drugs in children should be allowed.
pubmed:language
srp
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0370-8179
pubmed:author
pubmed:issnType
Print
pubmed:volume
123 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-4
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Therapeutics and clinical pharmacology of pediatric age].
pubmed:publicationType
Journal Article, English Abstract