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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-7-24
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pubmed:abstractText |
In two divisions of a chemical plant producing dust pesticides, employees exposed to dust, containing 28%-65% SiO2, were examined. In the first division (group I, 38 males and 35 females), the average air dust concentration was 5.0 mg/m3, and the active substances were: chlorinated hydrocarbons, captan, carbamates and dodine. In the other division (group II, 26 males and 33 females), the air dust concentration was 4.8-5.2 mg/m3, and the active substances included: carbamates, triazine compounds, cupric oxychloride, captan, lindane, carboxine. Spirographic investigations showed signs of pulmonary emphysema (RV/TLC) in 65.8% males and 60% females of group I and 38.5% males and 40.6% females of group II. In leucocyte concentrate smears, the cytochemical reactions to beta-glucuronidase, acid phosphatase and myeloperoxidase, as well as the nitroblue tetrazolinum (NBT)-dye reduction of neutrophils were performed. The random migration and chemotaxis of isolated neutrophils, washed or incubated in 10% autologous serum, their phagocytic activity and tube adherence test were also investigated. Compared to the controls, the reaction to beta-glucuronidase as well as the NBT reduction were increased, whereas the acid phosphatase and myeloperoxidase reactions were lowered. Impairment of neutrophil chemotaxis stimulated with zymozan-activated serum was observed in all groups of workers; random migration was enhanced in workers of group I and lowered in male workers of group II. Higher phagocytosis of latex particles occurred in workers of group I and in males of group II, while tube adhesion was impaired in group I and enhanced in males of group II.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0867-8383
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1819342-Adult,
pubmed-meshheading:1819342-Air Pollutants, Occupational,
pubmed-meshheading:1819342-Bronchitis,
pubmed-meshheading:1819342-Chemical Industry,
pubmed-meshheading:1819342-Chemotaxis, Leukocyte,
pubmed-meshheading:1819342-Chronic Disease,
pubmed-meshheading:1819342-Female,
pubmed-meshheading:1819342-Humans,
pubmed-meshheading:1819342-Incidence,
pubmed-meshheading:1819342-Male,
pubmed-meshheading:1819342-Middle Aged,
pubmed-meshheading:1819342-Neutrophils,
pubmed-meshheading:1819342-Occupational Diseases,
pubmed-meshheading:1819342-Pesticides,
pubmed-meshheading:1819342-Phagocytosis,
pubmed-meshheading:1819342-Respiratory Mechanics
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pubmed:year |
1991
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pubmed:articleTitle |
Neutrophil function in chemical plant workers employed in the production of dust pesticides.
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pubmed:affiliation |
Clinic of Gastroenterology, Silesian Medical Academy, Katowice, Poland.
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pubmed:publicationType |
Journal Article
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