rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2008-4-9
|
pubmed:abstractText |
Hepatitis B virus (HBV) infection induces an interaction of host immune responses against virus antigen-presenting hepatocytes. The emergence of mutants is a strategy through which the virus can escape host attacks and produce chronic infection. In this study, we aimed to investigate mutations of the human leukocyte antigen-A2-restricted T-cell epitope (TCE) in chronic HBV-infected children.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1572-0241
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
103
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1004-9
|
pubmed:meshHeading |
pubmed-meshheading:18190649-Adolescent,
pubmed-meshheading:18190649-Analysis of Variance,
pubmed-meshheading:18190649-Biological Markers,
pubmed-meshheading:18190649-Carcinoma, Hepatocellular,
pubmed-meshheading:18190649-Chi-Square Distribution,
pubmed-meshheading:18190649-Child,
pubmed-meshheading:18190649-Epitopes, T-Lymphocyte,
pubmed-meshheading:18190649-Female,
pubmed-meshheading:18190649-Follow-Up Studies,
pubmed-meshheading:18190649-Genotype,
pubmed-meshheading:18190649-Hepatitis B, Chronic,
pubmed-meshheading:18190649-Hepatitis B virus,
pubmed-meshheading:18190649-Humans,
pubmed-meshheading:18190649-Liver Neoplasms,
pubmed-meshheading:18190649-Longitudinal Studies,
pubmed-meshheading:18190649-Male,
pubmed-meshheading:18190649-Mutation
|
pubmed:year |
2008
|
pubmed:articleTitle |
Mutations of T-cell epitopes in the hepatitis B virus surface gene in children with chronic infection and hepatocellular carcinoma.
|
pubmed:affiliation |
Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|