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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-31
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pubmed:abstractText |
The nuclear receptor hepatic nuclear factor 4 alpha (HNF 4 alpha) is a master regulatory protein and an essential player in the control of a wide range of metabolic processes. Dysfunction of HNF 4 alpha is associated with metabolic disorders including diabetes. We were particularly interested in investigating molecular causes associated with diabetic nephropathy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1069-77
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pubmed:meshHeading |
pubmed-meshheading:18184923-Adolescent,
pubmed-meshheading:18184923-Age of Onset,
pubmed-meshheading:18184923-Animals,
pubmed-meshheading:18184923-Cell Line, Tumor,
pubmed-meshheading:18184923-Child,
pubmed-meshheading:18184923-Diabetes Mellitus, Type 2,
pubmed-meshheading:18184923-Diabetic Nephropathies,
pubmed-meshheading:18184923-Gene Expression Regulation,
pubmed-meshheading:18184923-Hepatocyte Nuclear Factor 4,
pubmed-meshheading:18184923-Humans,
pubmed-meshheading:18184923-Kidney,
pubmed-meshheading:18184923-Liver,
pubmed-meshheading:18184923-Rats,
pubmed-meshheading:18184923-Rats, Zucker,
pubmed-meshheading:18184923-TRPC Cation Channels
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pubmed:year |
2008
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pubmed:articleTitle |
HNF4 alpha and the Ca-channel TRPC1 are novel disease candidate genes in diabetic nephropathy.
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pubmed:affiliation |
Fraunhofer Institute of Toxicology and Experimental Medicine, Center of Molecular Medicine and Medical Biotechnology, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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