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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-12-31
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pubmed:abstractText |
Ataxia-telangiectasia (A-T) is an autosomal recessive disease characterized by neurological and immunological symptoms, radiosensitivity, and cancer predisposition. Heterozygous carriers of risk mutations in the A-T gene are predisposed to epithelial cancers. We initiated a study to elucidate the frequency and clinical relevance of ATM gene mutations in lung cancer patients of the young (LUCY) and compared the results with population-based control subjects from southwest Germany (KORA=Cooperative Health Research in the Region of Augsburg).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0188-4409
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
226-31
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pubmed:dateRevised |
2011-11-2
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pubmed:meshHeading |
pubmed-meshheading:18164969-Adolescent,
pubmed-meshheading:18164969-Adult,
pubmed-meshheading:18164969-Case-Control Studies,
pubmed-meshheading:18164969-Cell Cycle Proteins,
pubmed-meshheading:18164969-Child,
pubmed-meshheading:18164969-Child, Preschool,
pubmed-meshheading:18164969-DNA-Binding Proteins,
pubmed-meshheading:18164969-Female,
pubmed-meshheading:18164969-Follow-Up Studies,
pubmed-meshheading:18164969-Humans,
pubmed-meshheading:18164969-Lung Neoplasms,
pubmed-meshheading:18164969-Male,
pubmed-meshheading:18164969-Middle Aged,
pubmed-meshheading:18164969-Neoplasms, Glandular and Epithelial,
pubmed-meshheading:18164969-Point Mutation,
pubmed-meshheading:18164969-Polymorphism, Single Nucleotide,
pubmed-meshheading:18164969-Protein-Serine-Threonine Kinases,
pubmed-meshheading:18164969-Tumor Suppressor Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Detection of ATM gene mutations in young lung cancer patients: a population-based control study.
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pubmed:affiliation |
Institut und Poliklinik für Arbeits- und Sozialmedizin der Justus-Liebig Universität Giessen, Aulweg, Giessen, Germany. Joachim.Schneider@arbmed.med.uni-giessen.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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