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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-26
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pubmed:abstractText |
[2'-[(18)F]Fluoroethyl (lR-2-exo-3-exe)-8-methyl-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]-octane-2-carboxylate] ([(18)F]FECT) is a positron emission tomography (PET) tracer for imaging the dopamine transporter (DAT) in vivo. We report an improved radiosynthesis procedure and affinity data and have analyzed both brain tissue and plasma samples for the presence of radiometabolites as a function of time post intravenous injection of [(18)F]FECT to rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0969-8051
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pubmed:author |
pubmed-author:BexMarvaM,
pubmed-author:BormansGuyG,
pubmed-author:BussonRogerR,
pubmed-author:ChalonSylvieS,
pubmed-author:ChitneniSatish KSK,
pubmed-author:CleynhensBernardB,
pubmed-author:GarreauLucetteL,
pubmed-author:GuilloteauDenisD,
pubmed-author:HerveT YTY,
pubmed-author:Van LaereKoenK,
pubmed-author:VerbruggenAlfonsA,
pubmed-author:VermaelenPeterP
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75-82
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pubmed:meshHeading |
pubmed-meshheading:18158946-Animals,
pubmed-meshheading:18158946-Brain,
pubmed-meshheading:18158946-Chromatography, High Pressure Liquid,
pubmed-meshheading:18158946-Cocaine,
pubmed-meshheading:18158946-Dopamine Plasma Membrane Transport Proteins,
pubmed-meshheading:18158946-Fluorine Radioisotopes,
pubmed-meshheading:18158946-Ligands,
pubmed-meshheading:18158946-Male,
pubmed-meshheading:18158946-Radiopharmaceuticals,
pubmed-meshheading:18158946-Rats,
pubmed-meshheading:18158946-Rats, Wistar
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pubmed:year |
2008
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pubmed:articleTitle |
Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT.
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pubmed:affiliation |
Laboratory for Radiopharmacy, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, BE-3000, Leuven, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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