Linked Life Data

1815773

Source:http://linkedlifedata.com/resource/pubmed/id/1815773

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-6-29
pubmed:abstractText
The implantation of aortic allografts as well as stentless, freehand porcine xenograft valves requires proper sizing of the graft for the recipient aortic root. To visualize the aortic valve in motion and measure the cyclic expansion of the aortic root, we developed an isolated porcine heart model and a computerized three-dimensional reconstruction technique. Dynamic and static expansions of the aortic root were obtained from beating and arrested porcine hearts, and additional static expansions at varying pressures were measured from reconstructed three-dimensional models of valves obtained with high-resolution magnetic resonance imaging. Measurements of aortic root expansion have shown that it is highly dependent upon the pressures imposed on the heart. Although the aortic root expanded by only 5% between systolic pressures of 60 and 100 mmHg, the total expansion was up to 40% between rest and cyclic pressurizing to 100 mmHg. This data suggest that unstented xenograft valves should be sized 30% to 40% larger than the collapsed size of the recipient aorta. Proper sizing of valves on stents should also be attempted to reduce the large amount of leaflet redundancy that current stenting techniques produce.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0886-0440
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
482-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Aortic valve/root interactions in porcine hearts: implications for bioprosthetic valve sizing.
pubmed:affiliation
John P. Robarts Research Institute, University of Western Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't