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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1992-6-19
|
| pubmed:abstractText |
There is evidence that, for a number of chemicals, the elimination characteristics during bioconcentration do not follow monophasic first-order kinetics. In the first part of the present communication, a simple mathematical formula is presented that allows a clear-cut distinction between monophasic (pseudo-) and first-order and morephasic or higher-order elimination processes. The second part gives the mathematical description of a simple monophasic pseudo-first-order two-compartment model, which allows a quantitative kinetic analysis in the case of both initial compound and metabolite elimination.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0048-9697
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
109-110
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
395-405
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1815360-Animals,
pubmed-meshheading:1815360-Chlorobenzenes,
pubmed-meshheading:1815360-Fishes,
pubmed-meshheading:1815360-Hexachlorobenzene,
pubmed-meshheading:1815360-Kinetics,
pubmed-meshheading:1815360-Mathematics,
pubmed-meshheading:1815360-Models, Biological,
pubmed-meshheading:1815360-Structure-Activity Relationship,
pubmed-meshheading:1815360-Xenobiotics
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
First-order and pseudo-first-order elimination kinetics.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|