|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-1-16
|
|
pubmed:abstractText |
Selective inhibition of Na(+)/H(+) exchanger (NHE) improves organ dysfunctions including heart ischemia-reperfusion injury. In vivo and in vitro studies were designed to investigate whether NHE inhibitor has a protective effect in lethal acute liver failure, and if so, what are the mechanisms involved.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0168-8278
|
|
pubmed:author |
pubmed-author:HijikawaTakeshiT,
pubmed-author:IshizakiMorihikoM,
pubmed-author:ItoSeijiS,
pubmed-author:KaiboriMasakiM,
pubmed-author:KamiyamaYasuoY,
pubmed-author:MatsuiKosukeK,
pubmed-author:NishizawaMikioM,
pubmed-author:OkumuraTadayoshiT,
pubmed-author:OzakiTakashiT,
pubmed-author:TanakaHironoriH,
pubmed-author:TokuharaKatsujiK,
pubmed-author:UchidaYoichiroY,
pubmed-author:YamadaMasanoriM
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
48
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
289-99
|
|
pubmed:meshHeading |
pubmed-meshheading:18096265-Animals,
pubmed-meshheading:18096265-Enzyme Induction,
pubmed-meshheading:18096265-Guanidines,
pubmed-meshheading:18096265-Interleukin-10,
pubmed-meshheading:18096265-Liver,
pubmed-meshheading:18096265-Liver Failure, Acute,
pubmed-meshheading:18096265-Male,
pubmed-meshheading:18096265-NF-kappa B,
pubmed-meshheading:18096265-Nitric Oxide Synthase Type II,
pubmed-meshheading:18096265-Rats,
pubmed-meshheading:18096265-Rats, Sprague-Dawley,
pubmed-meshheading:18096265-Receptors, Interleukin-1,
pubmed-meshheading:18096265-Sodium-Hydrogen Antiporter,
pubmed-meshheading:18096265-Thiophenes,
pubmed-meshheading:18096265-Tumor Necrosis Factor-alpha,
pubmed-meshheading:18096265-Up-Regulation
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Na+/H+ exchanger inhibitor, FR183998, has protective effect in lethal acute liver failure and prevents iNOS induction in rats.
|
|
pubmed:affiliation |
Department of Surgery, Kansai Medical University, Moriguchi, Osaka, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
