Source:http://linkedlifedata.com/resource/pubmed/id/18084263
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2007-12-17
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pubmed:abstractText |
Mrug et al. propose that innate immunity is a hallmark of progressive polycystic kidney disease (PKD). We propose that innate immunity is a driving force in the progression of many renal diseases. Renal epithelial cells are capable of expressing a large variety of proinflammatory genes resulting in the production of cytokines, chemokines, cell-adhesion molecules, and complement components. We suggest that future therapeutic interventions should be directed toward control of innate immunity in renal disease.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0085-2538
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18084263-Cell Adhesion Molecules,
pubmed-meshheading:18084263-Chemokines,
pubmed-meshheading:18084263-Complement System Proteins,
pubmed-meshheading:18084263-Cytokines,
pubmed-meshheading:18084263-Disease Progression,
pubmed-meshheading:18084263-Humans,
pubmed-meshheading:18084263-Immunity, Innate,
pubmed-meshheading:18084263-Kidney Diseases
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pubmed:year |
2008
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pubmed:articleTitle |
Innate immunity as a driving force in renal disease.
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pubmed:affiliation |
Department of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands. e.de_heer@lumc.nl
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pubmed:publicationType |
Journal Article,
Comment
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