Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1992-5-21
pubmed:abstractText
Two experiments were conducted to study the uptake of beta-carotene in plasma, lipoproteins, and blood cells in pigs (50 to 55 kg; n = 40) after an i.m. injection of 0, 10, 20, or 40 mg of beta-carotene. Blood was sampled at 0, 3, 6, 12, 24, and 48 h postinjection. beta-Carotene was not detectable in plasma, lipoproteins, or blood cells of control pigs. However, concentrations of beta-carotene in plasma and lipoproteins increased in a dose-related manner in injected animals. Distribution of beta-carotene in the lipoproteins changed with time postinjection. The beta-carotene associated with very low density lipoproteins increased and that in low density lipoproteins decreased with time in treated pigs. Concentrations of beta-carotene in lymphocytes of treated pigs also increased within 3 h postinjection. The profile of beta-carotene in lymphocytes was different from that observed in plasma and lipoproteins. Carotene was not detectable in neutrophils and erythrocytes. Treatment did not alter concentrations of retinol or alpha-tocopherol in plasma, lipoproteins, or blood cells. Therefore, lymphocytes specifically take up beta-carotene, thereby suggesting a possible role of beta-carotene in this immune cell.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0021-8812
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4883-91
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Kinetic characteristics of beta-carotene uptake after an injection of beta-carotene in pigs.
pubmed:affiliation
Dept. of Anim. Sci. Washington State University, Pullman 99164-6320.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't