Linked Life Data

18074808

Source:http://linkedlifedata.com/resource/pubmed/id/18074808

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-12-13
pubmed:abstractText
Using two models of the acute normobaric hypercapnic hypoxia (ANHH) and acute normobaric hypoxia without hypercapnia (ANWH), some parameters of the impulse activity of somatosensory cortex neurons were studied in experiments on cats. A new antihypoxant drug--aminothiol complex substance composed of zinc(II) and N-acetyl-L-cysteine (piQ-1104, 50 mg/kg)--was used for the brain protection. The substance studied showed a high antihypoxant activity in the brain neurons during all stages of both ANHH and AHWH. The average active survival time during hypoxic state was increased 2-2.5 times in comparison to the control group. The neuron activity dynamics under ANHH and AHWH conditions and after piQ-1104 injection was observed.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0869-2092
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-51
pubmed:meshHeading
pubmed:articleTitle
[Antihypoxant effect of zinc(II) bis(N-acetyl-L-cysteinato)sulfate octahydrate in acute normobaric hypoxia].
pubmed:publicationType
Journal Article, English Abstract