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rdf:type |
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lifeskim:mentions |
umls-concept:C0001443,
umls-concept:C0020429,
umls-concept:C0034693,
umls-concept:C0043167,
umls-concept:C0243192,
umls-concept:C0332803,
umls-concept:C0392756,
umls-concept:C0597357,
umls-concept:C1181031,
umls-concept:C1314792,
umls-concept:C1522240
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pubmed:issue |
5
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pubmed:dateCreated |
2007-12-12
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pubmed:abstractText |
Activation of A1 adenosine receptors (A1Rs) causes antinociception after nerve injury and inflammation. However, the role of A2a adenosine receptors (A2aRs) for pain processing is less clear. In the current study, the authors investigated the role of spinal adenosine A1Rs and A2aRs for the maintenance of mechanical hyperalgesia in an animal model for postoperative pain.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
797-806
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18073555-Adenosine,
pubmed-meshheading:18073555-Adenosine A1 Receptor Agonists,
pubmed-meshheading:18073555-Adenosine A2 Receptor Agonists,
pubmed-meshheading:18073555-Adenosine-5'-(N-ethylcarboxamide),
pubmed-meshheading:18073555-Animals,
pubmed-meshheading:18073555-Disease Models, Animal,
pubmed-meshheading:18073555-Dose-Response Relationship, Drug,
pubmed-meshheading:18073555-GTP-Binding Proteins,
pubmed-meshheading:18073555-Hyperalgesia,
pubmed-meshheading:18073555-Male,
pubmed-meshheading:18073555-Pain, Postoperative,
pubmed-meshheading:18073555-Pertussis Toxin,
pubmed-meshheading:18073555-Phenylisopropyladenosine,
pubmed-meshheading:18073555-Physical Stimulation,
pubmed-meshheading:18073555-Potassium Channel Blockers,
pubmed-meshheading:18073555-Potassium Channels,
pubmed-meshheading:18073555-Rats,
pubmed-meshheading:18073555-Rats, Sprague-Dawley,
pubmed-meshheading:18073555-Surgical Procedures, Operative,
pubmed-meshheading:18073555-Vasodilator Agents
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pubmed:year |
2007
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pubmed:articleTitle |
Adenosine A1 but not A2a receptor agonist reduces hyperalgesia caused by a surgical incision in rats: a pertussis toxin-sensitive G protein-dependent process.
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pubmed:affiliation |
Department for Anaesthesiology and Operative Intensive Care, University of Muenster, Muenster, Germany. schmerz@uni-muenster.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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