pubmed-article:18061610 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0019163 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0011306 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0086222 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0439801 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0442726 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
pubmed-article:18061610 | lifeskim:mentions | umls-concept:C1705733 | lld:lifeskim |
pubmed-article:18061610 | pubmed:issue | 1-2 | lld:pubmed |
pubmed-article:18061610 | pubmed:dateCreated | 2008-1-29 | lld:pubmed |
pubmed-article:18061610 | pubmed:abstractText | Hepatitis B surface antigen (HBsAg)-specific T cells were analysed in 16 healthy individuals vaccinated against hepatitis B, using optimised protocols. HBsAg-specific IFN-gamma producing CD4(+) T cells were found at a similar low frequency (0.01%) within the naive T cell subset, the central and the effector memory T cell subset. Overall, HBsAg-specific total CD4(+) T cells were detected in approximately 81% of the HBV vaccinees. The use of dendritic cells substantially increased the otherwise low proliferative responses but not the percentage of IFN-gamma producing cells. The analysis of readily detectable CMV-specific CD4(+) T cell responses was used as a positive control and confirmed the adequacy of our assays. T cell responses associated with (in-) adequate hepatitis B vaccination can now be analysed in more detail. | lld:pubmed |
pubmed-article:18061610 | pubmed:language | eng | lld:pubmed |
pubmed-article:18061610 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18061610 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:18061610 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18061610 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18061610 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18061610 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18061610 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:18061610 | pubmed:month | Jan | lld:pubmed |
pubmed-article:18061610 | pubmed:issn | 0022-1759 | lld:pubmed |
pubmed-article:18061610 | pubmed:author | pubmed-author:BaanCarla CCC | lld:pubmed |
pubmed-article:18061610 | pubmed:author | pubmed-author:BetjesMichiel... | lld:pubmed |
pubmed-article:18061610 | pubmed:author | pubmed-author:LitjensNicoll... | lld:pubmed |
pubmed-article:18061610 | pubmed:author | pubmed-author:van... | lld:pubmed |
pubmed-article:18061610 | pubmed:author | pubmed-author:HuismanMartin... | lld:pubmed |
pubmed-article:18061610 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:18061610 | pubmed:day | 31 | lld:pubmed |
pubmed-article:18061610 | pubmed:volume | 330 | lld:pubmed |
pubmed-article:18061610 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:18061610 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:18061610 | pubmed:pagination | 1-11 | lld:pubmed |
pubmed-article:18061610 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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pubmed-article:18061610 | pubmed:year | 2008 | lld:pubmed |
pubmed-article:18061610 | pubmed:articleTitle | Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: limited usefulness of dendritic cells as signal enhancers. | lld:pubmed |
pubmed-article:18061610 | pubmed:affiliation | Department of Internal Medicine, Division of Nephrology, Erasmus Medical Center, Rotterdam, The Netherlands. n.litjens@erasmusmc.nl | lld:pubmed |
pubmed-article:18061610 | pubmed:publicationType | Journal Article | lld:pubmed |
entrez-gene:920 | entrezgene:pubmed | pubmed-article:18061610 | lld:entrezgene |
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