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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1992-5-6
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pubmed:abstractText |
Gossypol (I) and its derivatives gossylic nitrile-1,1'-diacetate (II), gossylic iminolactone (III) and gossylic lactone (IV) inhibit the replication of human immunodeficiency virus type 1 in vitro in the order III greater than I greater than II,IV, indicating that derivatives of gossypol can retain antiviral activities. All of the derivatives are less cytotoxic than gossypol.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
1043-6618
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
407-12
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
1991
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pubmed:articleTitle |
Inhibition of human immunodeficiency virus type I replication by derivatives of gossypol.
|
pubmed:affiliation |
Department of Biochemistry, University of New Mexico School of Medicine, Albuquerque 87131.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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